FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * CIALLELLA SUSAN STRANAHAN   2. Issuer Name and Ticker or Trading Symbol ISOLAGEN INC [ILE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner _____ Officer (give title below) __X__ Other (specify below) Former Director and Officer (Last) (First) (Middle) 107 STONEPINE DRIVE 3. Date of Earliest Transaction (Month/Day/Year) 06/12/2007 (Street) KENNETT SQUARE, PA 19348 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Employee Stock Option (Right to Buy)

$ 1.89

(1)

04/13/2016

Common Stock

160,000

160,000

D

Employee Stock Option (Right to Buy)

$ 4.7

(2)

04/28/2015

Common Stock

300,000

460,000

D

Employee Stock Option (Right to Buy)

$ 1.88

(3)

06/05/2016

Common Stock

300,000

760,000

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
CIALLELLA SUSAN STRANAHAN 107 STONEPINE DRIVE KENNETT SQUARE, PA 19348				Former Director and Officer

Signatures

/s/ Susan Stranahan Ciallella		06/12/2007
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The reported transactions involved amendments and modifications to certain outstanding option grants. The Company and Ms. Ciallella entered into a Settlement Agreement and Release, dated as of June 8, 2007 (the "Settlement Agreement"). Under the original terms of this option grant, the option was to vest in 12 equal installments on a quarterly basis over a three year period commencing July 13, 2006. Pursuant to the terms of the Settlement Agreement, the amount is fully vested and will expire 10 years from the date of its original issue date.
(2)	This option is fully vested and will expire 10 years from the date of its original issue date. The terms of this option was not modified by the Settlement Agreement.
(3)	Pursuant to the terms of the Settlement Agreement, the number of shares of the Company's common stock subject to the June 2006 Non-Qualified Stock Option grant was reduced from 400,000 to 300,000 shares, This option is fully vested and will expire 10 years from the date of its original issue date.

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