Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
CIALLELLA SUSAN STRANAHAN
  2. Issuer Name and Ticker or Trading Symbol
ISOLAGEN INC [ILE]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
_____ Officer (give title below) __X__ Other (specify below)
Former Director and Officer
(Last)
(First)
(Middle)
107 STONEPINE DRIVE
3. Date of Earliest Transaction (Month/Day/Year)
06/12/2007
(Street)

KENNETT SQUARE, PA 19348
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy) $ 1.89               (1) 04/13/2016 Common Stock 160,000   160,000 D  
Employee Stock Option (Right to Buy) $ 4.7               (2) 04/28/2015 Common Stock 300,000   460,000 D  
Employee Stock Option (Right to Buy) $ 1.88               (3) 06/05/2016 Common Stock 300,000   760,000 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
CIALLELLA SUSAN STRANAHAN
107 STONEPINE DRIVE
KENNETT SQUARE, PA 19348
      Former Director and Officer

Signatures

 /s/ Susan Stranahan Ciallella   06/12/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The reported transactions involved amendments and modifications to certain outstanding option grants. The Company and Ms. Ciallella entered into a Settlement Agreement and Release, dated as of June 8, 2007 (the "Settlement Agreement"). Under the original terms of this option grant, the option was to vest in 12 equal installments on a quarterly basis over a three year period commencing July 13, 2006. Pursuant to the terms of the Settlement Agreement, the amount is fully vested and will expire 10 years from the date of its original issue date.
(2) This option is fully vested and will expire 10 years from the date of its original issue date. The terms of this option was not modified by the Settlement Agreement.
(3) Pursuant to the terms of the Settlement Agreement, the number of shares of the Company's common stock subject to the June 2006 Non-Qualified Stock Option grant was reduced from 400,000 to 300,000 shares, This option is fully vested and will expire 10 years from the date of its original issue date.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.