Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  MHRC II LLC
2. Date of Event Requiring Statement (Month/Day/Year)
12/31/2012
3. Issuer Name and Ticker or Trading Symbol
EMISPHERE TECHNOLOGIES INC [EMIS]
(Last)
(First)
(Middle)
40 WEST 57TH STREET, 24TH FLOOR
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW YORK, NY 10019
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 11,405,186
I (1) (2) (3)
See Footnotes (1) (2) (3)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Convertible Notes   (4) 09/26/2012(5) Common Stock 6,441,357 $ 3.78 I (3) (6) See Footnotes (3) (6)
Warrants (right to buy) 08/21/2009 08/21/2014 Common Stock 2,878,829 $ 0.7 I (3) (7) See Footnotes (3) (7)
Warrants (right to buy) 06/08/2010 08/21/2014 Common Stock 666,997 $ 2.9 I (3) (8) See Footnotes (3) (8)
Warrants (right to buy) 08/26/2010 08/26/2015 Common Stock 2,799,991 $ 1.26 I (3) (9) See Footnotes (3) (9)
Warrants (right to buy) 07/06/2011 07/06/2016 Common Stock 2,578,582 $ 1.09 I (3) (10) See Footnotes (3) (10)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
MHRC II LLC
40 WEST 57TH STREET
24TH FLOOR
NEW YORK, NY 10019
    X    

Signatures

MHRC II LLC By: /s/ Janet Yeung Name: Janet Yeung Title: Authorized Signatory 01/10/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This Form 3 is being filed to report that MHRC II LLC, a Delaware limited liability company ("MHRC II"), became a beneficial owner of greater than 10% of the outstanding shares of common stock (the "Common Stock") of Emisphere Technologies, Inc. (the "Issuer") solely as a result of a transfer of Mark H. Rachesky, M.D.'s ("Dr. Rachesky") membership interests in MHR Institutional Advisors II LLC, a Delaware limited liability company ("Institutional Advisors II") to MHRC II.
(2) These shares of Common Stock consist of (i) 3,240,750 shares of Common Stock held for the account of MHR Institutional Partners II LP, a Delaware limited partnership ("Institutional Partners II"), and (ii) 8,164,436 shares of Common Stock held for the account of MHR Institutional Partners IIA LP, a Delaware limited partnership ("Institutional Partners IIA", and, together with Institutional Partners II, the "Funds").
(3) Institutional Advisors II is the general partner of each of the Funds. In such capacity, Institutional Advisors II may be deemed to beneficially own the shares of Common Stock held for the account of each of the Funds. MHRC II is the managing member of Institutional Advisors II. In such capacity, MHRC II may be deemed to beneficially own the shares of Common Stock held for the account of each of the Funds.
(4) Convertible Notes are exercisable immediately upon receipt thereof by the Reporting Persons.
(5) The maturity date under the Convertible Notes was on September 26, 2012. As reported by the Issuer on Form 8-K, dated September 26, 2012, the Issuer did not pay the amounts due and payable under the Convertible Notes on the maturity date.
(6) These Convertible Notes are convertible into (i) 1,830,292 shares of Common Stock that can be obtained by Institutional Partners II, and (ii) 4,611,065 shares of Common Stock that can be obtained by Institutional Partners IIA.
(7) These warrants are exercisable into (i) 818,011 shares of Common Stock that can be obtained by Institutional Partners II, and (ii) 2,060,818 shares of Common Stock that can be obtained by Institutional Partners IIA.
(8) These warrants are exercisable into (i) 189,525 shares of Common Stock that can be obtained by Institutional Partners II, and (ii) 477,472 shares of Common Stock that can be obtained by Institutional Partners IIA.
(9) These warrants are exercisable into (i) 795,610 shares of Common Stock that can be obtained by Institutional Partners II, and (ii) 2,004,381 shares of Common Stock that can be obtained by Institutional Partners IIA.
(10) These warrants are exercisable into (i) 732,696 shares of Common Stock that can be obtained by Institutional Partners II, and (ii) 1,845,886 shares of Common Stock that can be obtained by Institutional Partners IIA.

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