Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Boxer Capital, LLC
   2. Issuer Name and Ticker or Trading Symbol
Mirati Therapeutics, Inc. [MRTX] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
11682 EL CAMINO REAL, SUITE 320, 		 3. Date of Earliest Transaction (Month/Day/Year)
01/06/2017
(Street)

SAN DIEGO, CA 92130		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 01/06/2017   P   280,059 A $ 5.6 1,037,994 D (1) (2)  
Common Stock 01/06/2017   P   6,104 A $ 5.6 435,444 D (3)  
Common Stock               30,518 D (4)  
Common Stock               13,131 D (5)  
Common Stock               37,241 D (6)  
Common Stock               77,038 D (7)  
Common Stock               87,052 D (8)  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrant (right to purchase) $ 0.001 01/06/2017   P   2,341,786   01/06/2017   (9) Common Stock 2,341,786 $ 5.599 2,341,786 D (1) (2)  
Warrant (right to purchase) $ 0.001 01/06/2017   P   51,047   01/06/2017   (9) Common Stock 51,047 $ 5.599 51,047 D (3)  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Boxer Capital, LLC
11682 EL CAMINO REAL, SUITE 320
SAN DIEGO, CA 92130		     X    
LEWIS JOSEPH
C/O CAY HOUSE P.O. BOX N-7776
E.P. TAYLOR DRIVE LYFORD CAY
NEW PROVIDENCE, C5 		     X    
Boxer Asset Management Inc.
C/O CAY HOUSE P.O. BOX N-7776
E.P. TAYLOR DRIVE LYFORD CAY
NEW PROVIDENCE, C5 		     X    
MVA Investors, LLC
11682 EL CAMINO REAL, SUITE 320
SAN DIEGO, CA 92130		     X    
LAPPE RODNEY W
4660 LA JOLLA VILLAGE DRIVE, SUITE 500
SAN DIEGO, CA 92121		     X    
LIEBERBURG IVAN M
11682 EL CAMINO REAL, SUITE 320
SAN DIEGO, CA 92130		     X    
Davis Aaron I.
11682 EL CAMINO REAL, SUITE 320
SAN DIEGO, CA 92130		     X    
Reisman Neil
11682 EL CAMINO REAL, SUITE 320
SAN DIEGO, CA 92130		     X    
Dissanayake Shehan Bharatha
11682 EL CAMINO REAL, SUITE 320
SAN DIEGO, CA 92130		     X    
Fuglesang Christopher
11682 EL CAMINO REAL, SUITE 320
SAN DIEGO, CA 92130		     X    

Signatures

 Boxer Capital, LLC, By: /s/ Aaron Davis, Aaron Davis   01/10/2017
**Signature of Reporting Person Date
 Boxer Asset Management Inc., By: /s/ Jefferson Voss, Jefferson Voss   01/10/2017
**Signature of Reporting Person Date
 MVA Investors, LLC, By: /s/ Aaron Davis, Aaron Davis   01/10/2017
**Signature of Reporting Person Date
 Joseph Lewis, /s/ Joseph Lewis, Joseph Lewis   01/10/2017
**Signature of Reporting Person Date
 Rodney W. Lappe, By: /s/ Rodney W. Lappe, Rodney W. Lappe   01/10/2017
**Signature of Reporting Person Date
 Ivan M. Lieberburg, By: /s/ Ivan M. Lieberburg, Ivan M. Lieberburg   01/10/2017
**Signature of Reporting Person Date
 Aaron I. Davis, By: /s/ Aaron I. Davis, Aaron I. Davis   01/10/2017
**Signature of Reporting Person Date
 Neil Reisman, By: /s/ Neil Reisman, Neil Reisman   01/10/2017
**Signature of Reporting Person Date
 Shehan B. Dissanayake, By: /s/ Shehan B. Dissanayake, Shehan B. Dissanayake   01/10/2017
**Signature of Reporting Person Date
 Christopher Fuglesang, By: /s/ Christopher Fuglesang, Christopher Fuglesang   01/10/2017
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These securities are owned directly by Boxer Capital, LLC ("Boxer Capital"), which may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Braslyn Ltd. ("Braslyn"), (ii) Boxer Capital, (iii) Boxer Asset Management Inc. ("Boxer Management"), (v) MVA Investors, LLC ("MVA Investors"), (vi) Joe Lewis, (vii) Rodney W. Lappe, (viii) Ivan M. Lieberburg, (ix) Aaron I. Davis, (x) Neil Reisman, (xi) Shehan B. Dissanayake, and (xii) Christopher Fuglesang (collectively, the "Boxer Group), and indirectly by Boxer Management and Messrs.
(2) (Continued from Footnote 1) Lewis, Fuglesang, Reisman, Lieberburg, Dissanayake and Davis, by virtue of their ownership in Boxer Capital. Each of Messrs. Fuglesang, Reisman, Lieberburg, Dissanayake and Davis is a member of Boxer Capital. Each member of the Boxer Group other than Boxer Capital disclaims beneficial ownership of these securities to the extent it or he does not have a pecuniary interest therein.
(3) These securities are owned directly and solely by MVA Investors, which has sole voting and dispositive power with respect to these securities. Each of Messrs. Fuglesang, Reisman, Lieberburg, Dissanayake and Davis is a member of MVA Investors. Each member of the Boxer Group other than MVA Investors disclaims beneficial ownership of these securities to the extent it or he does not have a pecuniary interest therein.
(4) These securities are owned directly by Christopher Fuglesang, who may be deemed to be a member of the Boxer Group, and includes 11,436 shares received in connection with the pro rata distribution by Boxer Capital to its members on March 16, 2016 (the "Boxer Capital Pro Rata Distribution").
(5) These securities are owned directly by Neil Reisman, who may be deemed to be a member of the Boxer Group, and includes 4,921 shares received in connection with the Boxer Capital Pro Rata Distribution.
(6) These securities are owned directly by Ivan M. Lieberburg, who may be deemed to be a member of the Boxer Group, and includes 34,981 shares received in connection with the Boxer Capital Pro Rata Distribution.
(7) These securities are owned directly by Shehan B. Dissanayake, who may be deemed to be a member of the Boxer Group, and includes 28,869 shares received in connection with the Boxer Capital Pro Rata Distribution.
(8) These securities are owned directly by Aaron I. Davis, who may be deemed to be a member of the Boxer Group, and includes 32,622 shares received in connection with the Boxer Capital Pro Rata Distribution.
(9) The warrants do not have an expiration date and are not exercisable to the extent that, following exercise of such warrants, the warrant holder and its affiliates would beneficially own more than 19.99% of the issuer's common stock.

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