SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
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SCHEDULE 13G/A
(Rule 13d-102)
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INFORMATION TO BE INCLUDED IN STATEMENTS PURSUANT TO RULES 13d-1(b), (c)
AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 2)*
NUVELO INC.
(Name of Issuer)
Common Stock, $.01 par value
(Title of Class of Securities)
67072M103
(CUSIP Number)
December 31, 2004
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:
[ ] Rule 13d-1(b)
[X] Rule 13d-1(c)
[ ] Rule 13d-1(d)
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* The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).
CUSIP No. 67072M103 Schedule 13G/A PAGE 2 OF 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
CLSP, L.P.
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
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(3) SEC USE ONLY
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(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
675,107
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
675,107
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(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
675,107
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(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
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(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
2.1%
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(12) TYPE OF REPORTING PERSON
PN
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CUSIP No. 67072M103 Schedule 13G/A PAGE 3 OF 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
CLSP II, L.P.
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
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(3) SEC USE ONLY
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(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
934,612
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
934,612
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(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
934,612
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(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
2.9%
-----------------------------------------------------------------------------
(12) TYPE OF REPORTING PERSON
PN
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CUSIP No. 67072M103 Schedule 13G/A PAGE 4 OF 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
CLSP/SBS I, L.P.
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
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(3) SEC USE ONLY
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(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
279,915
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
279,915
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(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
279,915
-----------------------------------------------------------------------------
(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
0.9%
-----------------------------------------------------------------------------
(12) TYPE OF REPORTING PERSON
PN
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CUSIP No. 67072M103 Schedule 13G/A PAGE 5 OF 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
CLSP/SBS II, L.P.
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
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(3) SEC USE ONLY
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(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
83,600
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
83,600
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(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
83,600
-----------------------------------------------------------------------------
(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
0.3%
-----------------------------------------------------------------------------
(12) TYPE OF REPORTING PERSON
PN
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CUSIP No. 67072M103 Schedule 13G/A PAGE 6 OF 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Cooper Hill Partners, L.P.
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
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(3) SEC USE ONLY
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(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
654,179
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
654,179
-----------------------------------------------------------------------------
(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
654,179
-----------------------------------------------------------------------------
(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
2.0%
-----------------------------------------------------------------------------
(12) TYPE OF REPORTING PERSON
PN
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CUSIP No. 67072M103 Schedule 13G/A PAGE 7 OF 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Cooper Hill Partners, LLC
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
-----------------------------------------------------------------------------
(3) SEC USE ONLY
-----------------------------------------------------------------------------
(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
1,973,234
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
1,973,234
-----------------------------------------------------------------------------
(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
1,973,234
-----------------------------------------------------------------------------
(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
6.1%
(12) TYPE OF REPORTING PERSON
OO
-----------------------------------------------------------------------------
CUSIP No. 67072M103 Schedule 13G/A PAGE 8 OF 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Casdin Capital, LLC
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
-----------------------------------------------------------------------------
(3) SEC USE ONLY
-----------------------------------------------------------------------------
(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
2,627,413
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
2,627,413
-----------------------------------------------------------------------------
(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
2,627,413
-----------------------------------------------------------------------------
(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
8.2%
-----------------------------------------------------------------------------
(12) TYPE OF REPORTING PERSON
OO
-----------------------------------------------------------------------------
CUSIP No. 67072M103 Schedule 13G/A PAGE 9 of 16
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(1) NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Jeffrey Casdin
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) [ ]
(b) [x]
-----------------------------------------------------------------------------
(3) SEC USE ONLY
-----------------------------------------------------------------------------
(4) CITIZENSHIP OR PLACE OF ORGANIZATION
United States
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
0
SHARES --------------------------------------------------------------
BENEFICIALLY (6) SHARED VOTING POWER
2,627,413
OWNED BY --------------------------------------------------------------
EACH (7) SOLE DISPOSITIVE POWER
0
REPORTING --------------------------------------------------------------
PERSON WITH (8) SHARED DISPOSITIVE POWER
2,627,413
-----------------------------------------------------------------------------
(9) AGGREGATE AMOUNT BENEFICIALLY OWNED
BY EACH REPORTING PERSON
2,627,413
-----------------------------------------------------------------------------
(10) CHECK BOX IF THE AGGREGATE AMOUNT
IN ROW (9) EXCLUDES CERTAIN SHARES [ ]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED
BY AMOUNT IN ROW (9)
8.2%
-----------------------------------------------------------------------------
(12) TYPE OF REPORTING PERSON
IN
-----------------------------------------------------------------------------
CUSIP No. 67072M103 Schedule 13G/A PAGE 10 OF 16
ITEM 1(a). NAME OF ISSUER:
NUVELO INC.
ITEM 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
675 Almanor Avenue Sunnyvale, CA 94085
ITEM 2(a). NAME OF PERSON FILING:
This statement is filed by:
(i) CLSP, L.P. ("CLSP"),
a Delaware limited partnership, with respect to the Securities
owned by it;
(ii) CLSP II, L.P. ("CLSP II") a Delaware limited partnership, with
respect to the Securities owned by it;
(iii) CLSP/SBS I, L.P. ("CLSP/SBS I") a Delaware limited partnership,
with respect to the Securities owned by it;
(iv) CLSP/SBS II, L.P. ("CLSP/SBS II") a Delaware limited partnership,
with respect to the Securities owned by it;
(v) Cooper Hill Partners, L.P., a Delaware limited partnership with
respect to the Securities held for CLSP Overseas, Ltd. ("CLSP
Overseas"), [a Cayman Islands exempted company];
(vi) Cooper Hill Partners, LLC ("Cooper, LLC "), a Delaware limited
liability company and the sole general partner of CLSP, CLSP II,
CLSP/SBS I AND CLSP/SBS II with respect to the Securities owned by
CLSP, CLSP II, CLSP/SBS I AND CLSP/SBS II;
(vii) Casdin Capital, L.L.C. ("Casdin, LLC"), a Delaware limited
liability company and the sole general partner of Cooper Hill
Partners, L.P. and the managing member to Cooper, LLC with
respect to the Securities owned by CLSP, CLSP II, CLSP/SBS I and
CLSP/SBS II and CLSP Overseas; and
(viii) Jeffrey Casdin a citizen of the United States, and the Managing
Member of Casdin Capital, LLC, the general partner of Cooper Hill
Partners, L.P. and the managing member of Cooper LLC, with respect
to Securities subject to the control of Cooper LLC and Cooper Hill
Partners, LP.
The foregoing persons (other than CLSP Overseas) are hereinafter
sometimes collectively referred to as the "Reporting Persons." Any
disclosures herein with respect to persons other than the
Reporting Persons are made on information and belief after making
inquiry to the appropriate party.
CUSIP No. 67072M103 Schedule 13G/A PAGE 11 OF 16
ITEM 2(b). ADDRESS OF PRINCIPAL OFFICE OR, IF NONE, RESIDENCE:
The business address of each of the Reporting Persons is 767 Third
Avenue, New York, New York 10017. The business address of CLSP Overseas is c/o
Goldman Sachs (Cayman) Trust, Limited P.O. Box 896 G.T. Harbour Centre, Second
Floor North Church Street George Town, Grand Cayman Cayman Islands, B.W.I.
ITEM 2(c). CITIZENSHIP:
Cooper, LLC and Casdin, LLC are Delaware limited liability companies
and CLSP, CLSP II, CLSP/SBS I, CLSP/SBS II and Cooper Hill Partners, L.P. are
each a Delaware limited partnership. CLSP Overseas is a Cayman Islands
exempted company. Jeffrey Casdin is a citizen of the United States.
ITEM 2(d). TITLE OF CLASS OF SECURITIES: Common Stock, $.01 par value
ITEM 2(e). CUSIP NUMBER: 67072M103
ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO 13d-1(b) OR 13d-2(b) OR (c),
CHECK WHETHER THE PERSON FILING IS A:
(a) [ ] Broker or dealer registered under Section 15 of the Act
(b) [ ] Bank as defined in Section 3(a)(6) of the Act
(c) [ ] Insurance Company as defined in Section 3(a)(19) of the
Act
(d) [ ] Investment Company registered under Section 8 of the
Investment Company Act of 1940
(e) [ ] Investment Adviser registered under Section 203 of the
Investment Advisers Act of 1940: see Rule
13d-1(b)(1)(ii)(E)
(f) [ ] Employee Benefit Plan, Pension Fund which is subject to
the provisions of the Employee Retirement Income Security
Act of 1974 or Endowment Fund; see Rule 13d-1(b)(1)(ii)(F)
(g) [ ] Parent Holding Company, in accordance with Rule
13d-1(b)(ii)(G);
(h) [ ] Savings Associations as defined in Section 3(b) of the
Federal Deposit Insurance Act;
(i) [ ] Church Plan that is excluded from the definition of an
investment company under Section 3(c)(14) of the Investment
Company Act of 1940;
CUSIP No. 67072M103 Schedule 13G/A PAGE 12 OF 16
(j) [ ] Group, in accordance with Rule 13d-1(b)(1)(ii)(J).
IF THIS STATEMENT IS FILED PURSUANT TO Rule 13d-1(c),
CHECK THIS BOX. [x]
ITEM 4. OWNERSHIP.
A. CLSP
(a) Amount beneficially owned: 675,107
(b) Percent of class: 2.1%
(All percentages herein are based on 32,214,676 shares of Common Stock
reported to be outstanding as of October 29, 2004, as reflected in the
Company's quarterly report on Form 10-Q filed with the Securities and
Exchange Commission by the Company for the quarter ended September 30,
2004).
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
675,107
(iii) sole power to dispose or to direct the disposition of
0
(iv) shared power to dispose or to direct the disposition of
675,107
B. CLSP II
(a) Amount beneficially owned: 934,612
(b) Percent of class: 2.9%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
934,612
(iii) sole power to dispose or to direct the disposition of
0
(iv) shared power to dispose or to direct the disposition of
934,612
C. CLSP/SBS I
(a) Amount beneficially owned: 279,915
(b) Percent of class: 0.9%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
279,915
(iii) sole power to dispose or to direct the disposition of
0
CUSIP No. 67072M103 Schedule 13G/A PAGE 13 OF 16
(iv) shared power to dispose or to direct the disposition of
279,915
D. CLSP/SBS II
(a) Amount beneficially owned: 83,600
(b) Percent of class: 0.3%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
83,600
(iii) sole power to dispose or to direct the disposition of
0
(iv) shared power to dispose or to direct the disposition of
83,600
E. Cooper Hill Partners, L.P.
(a) Amount beneficially owned: 654,179
(b) Percent of class: 2.0%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
654,179
(iii) sole power to dispose or to direct the disposition of
0
(iv) shared power to dispose or to direct the disposition of
654,179
F. Cooper Hill Partners, LLC
(a) Amount beneficially owned: 1,973,234
(b) Percent of class: 6.1%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
1,973,234
(iii) sole power to dispose or to direct the disposition of
0
(iv) shared power to dispose or to direct the disposition of
1,973,234
CUSIP No. 67072M103 Schedule 13G/A PAGE 14 OF 16
G. Casdin Capital, LLC
(a) Amount beneficially owned: 2,627,413
(b) Percent of class: 8.2%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
2,627,413
(iii) sole power to dispose or to direct the disposition of
0
(iv) shared power to dispose or to direct the disposition of
2,627,413
H. Jeffrey Casdin
(a) Amount beneficially owned: 2,627,413
(c) Percent of class: 8.2%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote
0
(ii) shared power to vote or to direct the vote
2,627,413
(iii) sole power to dispose or to direct the disposition of
0
(iv) shared power to dispose or to direct the disposition of
2,627,413
ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
IF THIS STATEMENT IS BEING FILED TO REPORT THE FACT THAT AS OF THE
DATE HEREOF THE REPORTING PERSON HAS CEASED TO BE THE BENEFICIAL OWNER
OF MORE THAN 5% OF THE CLASS OF SECURITIES CHECK THE FOLLOWING [ ].
ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.
CLSP, CLSP II, CLSP/SBS I, and CLSP/SBS II are each private investment
partnerships, the sole general partner of which is Cooper, LLC. As the sole
general partner of CLSP, CLSP II, CLSP/SBS I, and CLSP/SBS II, Cooper, LLC
has the power to vote and dispose of the Securities owned by each of CLSP,
CLSP II, CLSP/SBS I, and CLSP/SBS II and, accordingly, may be deemed the
"beneficial owner" of such Securities. The managing member of Cooper, LLC is
Casdin, LLC of which Jeffrey Casdin is the sole member
Pursuant to an investment advisory contract, Cooper Hill Partners, L.P.
currently has the power to vote and dispose of the Securities held for the
account of CLSP Overseas and, accordingly, may be deemed the "beneficial
owner" of such Securities. Mr. Casdin is the sole member of Casdin, LLC, the
general partner of Cooper Hill Partners, L.P.
ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED
THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.
CUSIP No. 67072M103 Schedule 13G/A PAGE 15 OF 16
Not applicable.
ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not applicable.
ITEM 9. NOTICE OF DISSOLUTION OF GROUP.
Not applicable.
CUSIP No. 67072M103 Schedule 13G/A PAGE 16 OF 16
ITEM 10. CERTIFICATION. (if filing pursuant to Rule 13d-1(c))
Each of the Reporting Persons and CLSP Overseas, Ltd. hereby make the
following certification:
By signing below each Reporting Person certifies that, to the best of
its knowledge and belief, the securities referred to above were not acquired and
are not held for the purpose of or with the effect of changing or influencing
the control of the issuer of the Securities and were not acquired and not held
in connection with or as a participant in any transaction having that purpose or
effect.
SIGNATURES
After reasonable inquiry and to the best of our knowledge and belief, the
undersigned certify that the information set forth in this statement is true,
complete and correct.
DATED: February 14, 2005 /s/ Jeffrey Casdin,
JEFFREY CASDIN, individually, and on
behalf of CLSP, L.P., CLSP II, L.P.,
CLSP/SBS I, L.P., and CLSP/SBS II, L.P.
and as sole member of Casdin Capital,
L.L.C., the managing member of Cooper
Hill Partners, L.L.C. and the general
partner of Cooper Hill Partners, L.P.