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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the Securities
Exchange Act of 1934 (Amendment No.     )

	Filed by the Registrant   x
	Filed by a Party other than the Registrant   o
	Check the appropriate box:

	o   Preliminary Proxy Statement
	o   Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
	o   Definitive Proxy Statement
	x   Definitive Additional Materials
	o   Soliciting Material Pursuant to §240.14a-12

eXegenics Inc.

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(Name of Registrant as Specified In Its Charter)

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(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

      Payment of Filing Fee (Check the appropriate box):

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	3) Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee is calculated and state how it was determined):

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	o   Fee paid previously with preliminary materials.

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	2) Form, Schedule or Registration Statement No.:

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	4) Date Filed:

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SEC 1913 (02-02)	Persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

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FOR IMMEDIATE RELEASE

eXegenics Responds to Meyers-Weiss Claim

DALLAS, December 5, 2003 — eXegenics Inc. (Nasdaq: EXEG) said today it has received from the Meyers-Weiss Group copies of consents purporting to represent a majority of the outstanding shares of eXegenics voting stock, which would be sufficient to elect a dissident slate of directors. eXegenics said that it is engaging IVS Associates, Inc., independent proxy inspectors, to provide an independent tabulation of the consents and revocations and to report on the results as soon as possible. eXegenics said it would have further comment after it reviews the report from IVS.

Safe Harbor

This release contains forward-looking statements. The words “believe,” “expect,” “intend”, “anticipate,” variations of such words, and similar expressions identify forward-looking statements, but their absence does not mean that the statement is not forward-looking. These statements are subject to certain risks, uncertainties and assumptions that are difficult to predict. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release. eXegenics undertakes no obligation to update any forward-looking statement to reflect new information, events or circumstances after the date of this release or to reflect the occurrence of unanticipated events.