Vasopressin Antagonists Market to Reach USD 2.7 Bn by 2031 | TMR Study

WILMINGTON, DE / ACCESSWIRE / March 31, 2023 / Transparency Market Research Inc. - The global vasopressin antagonists market stood at USD 1.7 Bn in 2022 and the global market is projected to reach USD 2.7 Bn by 2031. The global industry is anticipated to expand at a CAGR of 4.9% between 2023 and 2031.

Transparency Market Research inc., Friday, March 31, 2023, Press release picture

Hyponatremia is a common electrolyte disorder that affects millions of people worldwide. The rising prevalence of hyponatremia is expected to drive the demand for vasopressin antagonists, as they are the primary treatment option for this condition.

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Market Snapshot:

Report Coverage Details
Market Revenue USD 1.7 Bn in 2022
Estimated Value USD 2.7 Bn by 2031
Growth Rate 4.9%
Forecast Period 2023-2031
No. of Pages 183 Pages
Market Segmentation By Drug Type, Application and Distribution Channel
Regions Covered North America, Europe, Asia Pacific, Middle East & Africa, South America
Companies Covered Otsuka, Cumberland Pharmaceuticals, Mayo Clinic, and Hopital du Sacre-Coeur de Montreal

The market value of the vasopressin antagonists is also increasing due to the growing incidence of heart failure. Heart failure is a chronic condition that affects a significant portion of the global population. Vasopressin antagonists are often prescribed as an add-on therapy for patients with heart failure, and the increasing incidence of heart failure is expected to boost the demand for these drugs in the near future.

Additionally, in recent years, several new vasopressin antagonists have been approved for use in different indications. These new drugs are expected to contribute significantly to the growth of the vasopressin antagonists market.

Furthermore, there has been a growing awareness about hyponatremia in recent years, which has led to an increase in the number of diagnoses. Hence, the increasing awareness about hyponatremia is one of the major factors that is likely to accelerate the market growth in the forthcoming years.

In addition, the geriatric population is more prone to conditions such as hyponatremia and heart failure, which are treated with vasopressin antagonists. The growing geriatric population is, therefore, expected to be a significant driver of the vasopressin antagonists market.

Besides, the development of new technologies and drug delivery systems is one of the major factors that is likely to create lucrative opportunities for the effectiveness and efficiency of vasopressin antagonists, further driving the growth of the market.

Also, there has been a significant increase in the research and development of vasopressin antagonists in recent years, which has led to the discovery of new drugs and indications. This increased R&D is expected to contribute significantly to the growth of the vasopressin antagonists market in the forthcoming years.

Key Findings of the Market Report

  • On the basis of drug type, tolvaptan is likely to be most preferred, due to its high efficacy in treating hyponatremia.
  • By application, treatment for nephrogenic diabetes insipidus (NDI) is expected to account for the maximum use of vasopressin antagonists
  • Based on distribution channel, hospital pharmacies will remain the primary point of sale for vasopressin antagonists

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Global Vasopressin Antagonists Market: Growth Drivers

  • The global vasopressin antagonists market is projected to expand at a steady pace from 2021 to 2031 due to the growing trend of personalized medicine, which involves tailoring treatment options to individual patients based on their genetic makeup.
  • Another factor that is projected to augment the market growth includes the favorable reimbursement policies for vasopressin antagonists in many countries, especially among patients who cannot afford them.
  • Additionally, rising partnerships and collaborations between pharmaceutical companies and research organizations is a major factor that is anticipated to fuel the market prospects in the near future.

Global Vasopressin Antagonists Market: Regional Landscape

  • North America is expected to lead the global market. The regional market is expected to witness significant growth in forthcoming years, attributed to the factors such as the high prevalence of hyponatremia and related conditions such as heart failure and liver cirrhosis.
  • Asia Pacific is likely to offer significant growth opportunities, amid a rise in the prevalence of euvolemic hyponatremia and syndrome of inappropriate secretion of antidiuretic hormone (SIADH)

Global Vasopressin Antagonists Market: Key Players

Some of the key market players in the global vasopressin antagonists market:

  • Otsuka
  • Cumberland Pharmaceuticals
  • Mayo Clinic
  • Hopital du Sacre-Coeur de Montreal

Competitive Landscape

Prominent players in the Vasopressin Antagonists Industry are taking advantage of the rapidly increasing demand for the Vasopressin Antagonists. To further their outreach, players are relying on collaborations, partnerships and acquisitions with existing small, medium and large-scale providers. Some prominent market developments are as follows:

  • In 2022, Roche announced the initiation of a Phase 2 trial for its investigational drug RG6185, a vasopressin V1a receptor antagonist, for the treatment of heart failure.
  • Subsequently, in the same year, Sanofi announced the initiation of a Phase 3 trial of SAT-814 for the treatment of patients with heart failure and preserved ejection fraction.
  • In 2021, Otsuka Pharmaceutical announced positive results from a Phase 3 trial of SAMSCA┬« (tolvaptan) for the treatment of hyponatremia in patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH).

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Global Vasopressin Antagonists Market: Segmentation

Drug Type

  • Vaprisol
  • Tolvaptan


  • Central Diabetes Insipidus
  • Nephrogenic Diabetes Insipidus
  • Other Applications

Distribution Channel

  • Retail Pharmacies
  • Hospital Pharmacies
  • Online Pharmacies


  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

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